Laboratory Animals > Volume 15, Number 1 > Pp. 13-20

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Comparative feeding trials of 2 maintenance diets containing different crude protein levels

Dorothea I. Connell, W. Street, R. Ann Pendry, J. Yeboah and A. Godfrey

Institute of Cancer Research: Royal Cancer Hospital, Fulham Road, London SW3 6JB, United Kingdom; Chester Beatty Research Institute, Fulham Road, London SW3 6JB, United Kingdom; Institute of Cancer Research: Royal Cancer Hospital, Fulham Road, London SW3 6JB, United Kingdom; Chester Beatty Research Institute, Fulham Road, London SW3 6JB, United Kingdom; Institute of Cancer Research: Royal Cancer Hospital, Fulham Road, London SW3 6JB, United Kingdom; Clifton Avenue, Belmont, Sutton, Surrey, SM2 5PX, United Kingdom; Institute of Cancer Research: Royal Cancer Hospital, Fulham Road, London SW3 6JB, United Kingdom; Chester Beatty Research Institute, Fulham Road, London SW3 6JB, United Kingdom; Institute of Cancer Research: Royal Cancer Hospital, Fulham Road, London SW3 6JB, United Kingdom; Chester Beatty Research Institute, Fulham Road, London SW3 6JB, United Kingdom

2 commercially-produced maintenance diets containing crude protein levels of 14-15 and 21% were offered to normal mice and normal and thymectomized rats for 48-52 weeks. Both sexes of 2 strains of mouse, CBA/Ca and BALB/c, and 2 strains of rat, Wistar males and Lister Hooded females, were used, starting at 8-10 weeks of age.

Results indicated that the diet containing 14-15% crude protein was an acceptable substitute for the 21% protein diet and could reduce the dietary cost by 30-40%.

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