Laboratory Animals > Volume 17, Number 1 > Pp. 13-17

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Brown fat tumours (hibernomas) in rats: histopathological and ultrastructural study

A. J. Al Zubaidy and J. P. Finn

Department of Pathology, Life Science Research, Stock, Essex, United Kingdom; Department of Pathology, College of Veterinary Medicine (Baghdad University), Amiria, Baghdad, Iraq

Brown fat tumours, 'hibernomas', are described in 2 Wistar and 1 CD rats; 2 were intrathoracic and 1 was interscapular. The incidence of hibernoma in rats undergoing carcinogenic bioassay at this laboratory over the 4 years between 1977-1981 is 3 in 3200. Clinical and autopsy findings and histological and ultrastructural observations are reported, and a review of the literature is presented.

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