Laboratory Animals > Volume 18, Number 1 > Pp. 42-44

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A modified anaesthetic vapour extraction system

Susan C. Hunter, J. B. Glen and C. J. Butcher

Bioscience Dept. II, Pharmaceuticals Division, Alderley Park, Macclesfield, Cheshire SK10 4TG, United Kingdom; Bioscience Dept. II, Pharmaceuticals Division, Alderley Park, Macclesfield, Cheshire SK10 4TG, United Kingdom; Pharmaceutical Department Imperial Chemical Industries PLC, Pharmaceuticals Division, Alderley Park, Macclesfield, Cheshire SK10 4TG, United Kingdom

A number of design modifications have been made to an extraction system for use with inhalation anaesthesia techniques in rats and other small laboratory animals. These changes necessitated a re-evaluation of the effectiveness of this equipment in limiting the operator's exposure to the anaesthetic vapours used. With a given fresh gas flow. the halothane vapour concentration in the operator's breathing zone was dependent on the design of the oronasal mask. With the optimum configuration the atmospheric concentration of halothane was less than 1 ppm.

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