Laboratory Animals > Volume 24, Number 1 > Pp. 48-52

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Glomerular lipidosis in a Syrian hamster of the APA strain

M. Norimatsu, K. Doi, S. Itagaki, K. Honjo and T. Mitsuoka

Department of Biomedical Science, Faculty of Agriculture, The University of Tokyo, Bunkyo, Tokyo 113, Japan; Department of Biomedical Science, Faculty of Agriculture, The University of Tokyo, Bunkyo, Tokyo 113, Japan; Department of Biomedical Science, Faculty of Agriculture, The University of Tokyo, Bunkyo, Tokyo 113, Japan; Department of Biomedical Science, Faculty of Agriculture, The University of Tokyo, Bunkyo, Tokyo 113, Japan; Department of Biomedical Science, Faculty of Agriculture, The University of Tokyo, Bunkyo, Tokyo 113, Japan

Spontaneous glomerular lipidosis was found in a 12-week-old male Syrian hamster of the APA strain. Lipids in the glomeruli were observed as droplets in a prominently expanded mesangial area and as emboli in a dilated capillary lumen. Lipid deposition was also, but less often, detected in tubular epithelial cells and interstitial cells around the lipid-laden glomeruli. This case of glomerular lipidosis was considered to be closely related to hyperglycaemia and hyperlipidaemia.

Key Words: GLOMERULAR LIPIDOSIS • APA HAMSTER

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