Laboratory Animals > Volume 25, Number 1 > Pp. 16-20

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Ambulatory electrocardiography (Holter monitoring) in caged monkeys

A. P. Vogel, G. P. Jaax, T. M. Tezak-Reid, S. I. Baskin and J. L. Bartholomew

Veterinary Medicine and Laboratory Resources Division, United States Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, Maryland 21010-5425, USA; Veterinary Medicine and Laboratory Resources Division, United States Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, Maryland 21010-5425, USA; Veterinary Medicine and Laboratory Resources Division, United States Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, Maryland 21010-5425, USA; Veterinary Medicine and Laboratory Resources Division, United States Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, Maryland 21010-5425, USA; Veterinary Medicine and Laboratory Resources Division, United States Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, Maryland 21010-5425, USA

A swivel-tethering and jacket system was used in conjunction with vinyl patch electrodes and Holter recorders to obtain continuous ECG recordings in 12 rhesus monkeys on a long-term (12 day) study. Animals were custom-fitted with nylon mesh jackets that were connected to a swivel unit by a flexible, stainless steel tether. Lead wires from the chest electrodes passed through the tether to the electrical swivel apparatus located at the top of the cage. Wires from the upper part of the swivel were attached to a reel-to-reel Holter recorder. This technique was used to obtain 24-h continuous ECG recordings, which were later processed using a computer-assisted Holter analysis system.

Key Words: AMBULATORY MONITORING • ELECTROCARDIOGRAPHY • MACACA SPECIES

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