Laboratory Animals > Volume 25, Number 1 > Pp. 35-39

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Isolation of Streptobacillus moniliformis from the middle ear of rats

J. P. Koopman, M. E. van den Brink, P. P. C. A. Vennix, W. Kuypers, R. Boot and R. H. Bakker

Central Animal Laboratory, Catholic University of Nijmegen, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands; Central Animal Laboratory, Catholic University of Nijmegen, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands; Department of Otorhinolaryngology, Catholic University of Nijmegen, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands; Department of Otorhinolaryngology, Catholic University of Nijmegen, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands; Department of Animal Supply, Laboratory for Parasitology and Mycology, National Institute of Public Health and Environmental Protection, P.O. Box 1, 3720 BA Bilthoven, The Netherlands; Department for Laboratory Animal Bacteriology, Laboratory for Parasitology and Mycology, National Institute of Public Health and Environmental Protection, P.O. Box 1, 3720 BA Bilthoven, The Netherlands; Department for Laboratory Animal Bacteriology, Laboratory for Parasitology and Mycology, National Institute of Public Health and Environmental Protection, P.O. Box 1, 3720 BA Bilthoven, The Netherlands

Streptobacillus moniliformis was isolated from the middle ear of 9 of 16 rats used for otological studies. Examination of rat sera for the presence of anti-Streptobacillus moniliformis antibodies using an ELISA technique resulted in 15 seropositive animals. The source of the S. moniliformis infection was not determined.

Key Words: ELISA • RATS • STREPTOBACILLUS MONILIFORMIS

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