Laboratory Animals > Volume 25, Number 4 > Pp. 287-290

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The incidence of Encephalitozoon cuniculi in a commercial barrier-maintained rabbit breeding colony

Gary Greenstein, Carla K. Drozdowicz, Felix G. Garcia and Leon L. Lewis

Department of Laboratory Animal Resources, Hoffmann-La Roche Inc., Nutley, New Jersey 07110, USA; Department of Laboratory Animal Resources, Hoffmann-La Roche Inc., Nutley, New Jersey 07110, USA; Department of Laboratory Animal Resources, Hoffmann-La Roche Inc., Nutley, New Jersey 07110, USA; Department of Laboratory Animal Resources, Hoffmann-La Roche Inc., Nutley, New Jersey 07110, USA

Between 1982 and 1987 sera from 4952 New Zealand White rabbits (Oryctolagus cuniculus) obtained from a single commercial supplier were tested for the presence of antibodies to Encephalitozoon cuniculi. A commercially available carbon immunoassay test kit was used. Initially 32·9% of the rabbits were seropositive with the number progressively decreasing to 2·3% by 1987. The reason for the significant decline in the incidence of infection was most likely due to a selection process for breeding stock instituted by the supplier based upon productivity, posture and weight of each animal.

Key Words: RABBIT • CARBON IMMUNOASSAY • E. CUNICULI

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