RSM logo
Laboratory Animals

Home Current issue Browse archive Alerts About the journal Feedback
 
This version was published on 1 October 2009
Lab Anim 2009;43:333-337
doi:10.1258/la.2009.0080030
© 2009 Laboratory Animals Limited

This Article
Right arrow Figures Only
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
la.2009.0080030v1
43/4/333    most recent
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Google Scholar
Right arrow Articles by Osorio-da Cruz, S M
Right arrow Articles by Walpoth, B
PubMed
Right arrow PubMed Citation
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?

Original Articles

Vascular ultrasound studies for the non-invasive assessment of vascular flow and patency in experimental surgery in the pig

S M Osorio-da Cruz 1 2 , Y Aggoun 3, M Cikirikcioglu 2, E Khabiri 2, K Djebaili 2, A Kalangos 2 and B Walpoth 2

1 Service of Cardiology, Department of Pediatrics, The Children's Hospital of Denver, University of Colorado Denver & Health Sciences Center Denver, Denver, CO, USA; 2 Geneva Cardiovascular Research Group; 3 Service of Cardiovascular Surgery, Department of Surgery and the Paediatric Cardiology Unit, Department of Paediatrics, Children's University Hospital of Geneva, Geneva, Switzerland

Corresponding author: S M Osorio-da Cruz, Service of Cardiology, Department of Pediatrics, The Children's Hospital of Denver, University of Colorado Denver & Health Sciences Center Denver, 13123 East 16th Avenue, Aurora, CO 80045, USA. Email: osoriolujan.suzanne{at}tchden.org

Vascular ultrasound is a reliable non-invasive tool used for the routine assessment of vascular flow and patency in human recipients. We describe the use at three different time points (immediately, 1 week and 4 weeks postsurgery) of ultrasound studies and its validation by angiographic studies in 37 swine undergoing carotid graft replacement. We calculated predictive values (>92%), sensitivity (>85%) and specificity (>92%) with high results at all time points. Ultrasound appeared as an accessible non-invasive technique, providing rapid, safe, repeatable and reliable results. It is an excellent alternative to angiography, avoiding risks inherent to invasive methods and therefore contributing to animal welfare.

Key Words: Swine • vascular ultrasound • non-invasive techniques • vascular angiography


Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?





  RSM Press eJournals Collection 2010