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This version was published on 1 October 2008
Lab Anim 2008;42:483-488
doi:10.1258/la.2007.007090
© 2008 Laboratory Animals Limited

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The effect of ketamine/xylazine and carbon dioxide on plasma luteinizing hormone releasing hormone and testosterone concentrations in the male Norway rat

E M Gould 

Health and Food Sector, HortResearch, East Street, PB 3123, Hamilton, New Zealand


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  		Figure 1 Testosterone concentration in male rat plasma pre-ketamine/xylazine anaesthesia, one hour (n = 9) and 24 h (n = 9) later and after euthanasia by CO2 (n = 4). Values are presented as the means of the treatment groups ± standard error of mean. Control is the pooled concentration of the preanaesthetic blood samples; one hour and 24 h are the concentrations of testosterone one and 24 h after anaesthesia, respectively, CO2 is the concentration of testosterone after CO2 euthanasia only

 

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  		Figure 2 Luteinizing hormone releasing hormone (LHRH) concentration in male rat plasma pre-ketamine/xylazine anaesthesia, one hour (n = 9) and 24 h (n = 9) later and after euthanasia by CO2 (n = 4). Values are presented as the means of the treatment groups ± standard error of mean. Control is the pooled concentration of the preanaesthetic blood samples; one hour and 24 h are the concentrations of LHRH one hour and 24 h after anaesthesia, respectively, CO2 is the concentration of LHRH after CO2 euthanasia only. *Denotes a significant difference between CO2 and control (P ≤ 0.05); **denotes a significant difference between KX24 + CO2 and control (P ≤ 0.01)

 

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