Laboratory Animals > Volume 43, Number 1 > Pp. 96-101

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Ventral recumbency is crucial for fast and safe orotracheal intubation in laboratory swine

M M Theisen ^1 * , M Maas ^1 *, M A Grosse Hartlage ¹, F Ploner ², S M Niehues ³, H K Van Aken ¹, T P Weber ¹ and J K Unger ⁴

¹ Department of Anaesthesiology and Intensive Care, Münster University Hospital, Albert-Schweitzer-Strasse 33, D-48149 Münster, Germany; ² Department of Anaesthesiology and Critical Care Medicine, Vipiteno Hospital, Vipiteno, Italy; ³ Department of Radiology; ⁴ Department of Experimental Medicine (FEM), Campus Virchow-Klinikum, Charité-Universitätsmedizin, Berlin, Germany

Corresponding author: Marc Michael Theisen. Email: theisen{at}anit.uni-muenster.de

The aim of this study was to find the fastest, easiest and safest method of achieving orotracheal intubation for general anaesthesia in laboratory pigs. Twenty-one Yorkshire x Landrace crossbreed male castrated pigs (32.9 ± 4.8 kg) were investigated. Dorsal and ventral recumbency are the alternatives most frequently described for animal positioning during intubation procedures. Based on standardized induction of general anaesthesia using pentobarbital and remifentanil, the dorsoventral and ventrodorsal positions were compared with regard to the time needed, changes in oxygenation and circulatory response. Positioning was found to be crucial for fast orotracheal intubation. The time required for safe intubation is significantly shorter with the ventrodorsal position (17.3 s) in comparison with the dorsoventral position (58.4 s; P < 0.001). Hypoxia did not occur in either group. A significant drop in systolic blood pressure was observed in both groups. Diastolic and mean arterial pressures were not influenced by intubation. A significant increase in heart rate was observed in pigs intubated in ventral recumbency, but not after intubation in the dorsal position. Preoxygenation before intubation is vitally important for preventing hypoxia. With regard to clinical practice, the haemodynamic changes observed in this investigation do not appear to be relevant, as the mean arterial pressure was not altered and heart rates only increased moderately. It may be concluded that the ventrodorsal position can be recommended for orotracheal intubation in pigs as the first choice for providing a smooth and fast airway.

Key Words: Pig • intubation • laryngoscopy • anaesthesia • experimental surgery

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